
Selected Publications
KL Flanagan. Will dual Japanese encephalitis and measles-rubella vaccination hinder measles and rubella eradication? Lancet Infect Dis 2019; pii: S1473-3099. PMID 30833161.
S Esposito, P Stefanelli, N Fry, G Fedele, Q He, P Paterson, T Tan, M Knuf, C Rodrigo, CW Olivier, KL Flanagan, I Hung, I Lutsar, K Edwards, M O’Ryan, N Principi. Pertussis prevention: reasons for resurgence, and differences in the current acellular pertussis vaccines? Front Immunol 2019; 10: 1344. PMID 31333640.
K Wilson, KL Flanagan, M Prakash, M Plebanski. Malaria vaccines in the eradication era: current status and the future pipeline. Exp Rev Vaccines 2019; 18(2): 133-151. PMID 30601095.
P Zimmermann, S Donath, K Perrett, N Messina, N Ritz, M Netea, KL Flanagan, F Van der Klis, N Curtis. The influence of neonatal Bacille Calmette-Guérin (BCG) immunisation on heterologous vaccine responses in infants. Vaccine 2019; 37(28): 3735-44. PMID 31153688.
B Freyne, S Donath, S Germano, K Gardiner, D Casalaz, RM Robins-Browne, N Amenyogbe, N Messina N, MG Netea, KL Flanagan, T Kollmann, N Curtis. The effect of neonatal BCG vaccination on cytokine responses to heterologous antigens in a randomised controlled trial. J Infect Dis 2018; 217(11): 1798-1808. PMID 29415180.
A Harper, KL Flanagan. Effect of Sex on Vaccination Outcomes: Important but Frequently Overlooked. Curr Opin Pharmacol 2018; 41: 122-7. PMID 29883854.
R Vemuri, KE Sylvia, SL Klein, SC Forster, M Plebanski, R Eri, KL Flanagan. The microgenderome revealed: sex differences in bidirectional interactions between the microbiota, hormones, immunity and disease susceptibility. Sem Immunopathol 2018; Epub. PMID 30298433.
KL Flanagan. Measles vaccination is effective at under nine months of age and provides non-specific immunological benefits. J Infect Dis 2017; 215(8): 1177-78. PMID 28368539.
KL Flanagan, AL Fink, M Plebanski, SL Klein. Sex and gender differences in the outcomes of vaccination over the life course. Ann Rev Cell Dev Biol 2017; 33: 577-99. PMID 28992436.
J Ndure, F Noho-Konteh, J Adetifa, M Cox, F Barker, MT Le, LC Sanyang, A Drammeh, H Whittle, E Clarke, M Plebanski, SL Rowland-Jones, KL Flanagan. Negative correlation between circulating CD4+FOXP3+CD127- regulatory T cells and subsequent antibody responses to infant measles vaccine but not diphtheria-tetanus-pertussis vaccine implies a regulatory role. Frontiers Immunol 2017; 8 (921): 1-12. PMID 28855899.
F Darboe, J Adetifa, J Reynolds, S Hossin, M Plebanski, MG Netea, SL Rowland-Jones, JS Sutherland, KL Flanagan. Minimal sex-differential modulation of reactivity to pathogens and Toll-like receptor ligands following infant BCG Russia vaccination. Frontiers Immunol 2017; 8: 1092. PMID 28951731.
M Plebanski, KL Flanagan. The economics of malaria vaccine development. Trends Parasitol 2017; 33(3): 154-6. PMID 28169112.
G Minigo, KL Flanagan, RM Slattery, M Plebanski. Vaccination with altered peptide ligands of a Plasmodium berghei circumsporozoite CD8 T-cell epitope: A model to generate T cells resistant to immune interference by polymorphic epitopes. Frontiers Immunol 2017; 8: 115. PMID 28261200.
J Tran, K Wilson, M Plebanski, KL Flanagan. Manipulating the microbiota to improve human health throughout life. Trans Roy Soc Trop Med Hyg 2017; 111(9): 379-81. PMID 29244178.
CM Bliss, G Bowyer, A Drammeh, I Nébié, YJ Jagne, N Edwards, MO Afolabi, AB Tiono,JB Yaro, JU Adetifa, SH Hodgson, NA Anagnostou, R Roberts,J Njie-Jobe, CJ Duncan, E Berrie, S Moyle, SC Gilbert, R Cortese, A Nicosia, NK Viebig, O Leroy, AM Lawrie, KL Flanagan, B Kampmann, P Bejon, EB Imoukhuede, SB Sirima, K Bojang, AVS Hill, KJ Ewer. Viral vector malaria vaccines induce high-level T cell and antibody responses in West African children and infants. Molec Ther 2017; 25(2): 547-59. PMID 28153101.
KJ Jensen, M Søndergaard, A Andersen, C Martins, C Erikstrup, P Aaby, KL Flanagan, CS Benn. Long-term sex-differential effects of neonatal vitamin A supplementation on in vitro cytokine responses. Brit J Nutrition 2017; 1-7. PMID 29166972.
SL Klein and KL Flanagan. Sex differences in the immune response. Nat Rev Immunol 2016; 16(10): 626-38. PMID 27546235.
E Fish, KL Flanagan, D Furman, SL Klein, TR Kollman, DL Jeppesen, O Levy, A Marchant, S Namachivaayam, MG Neta, M Plebanski, SL Rowland-Jones, LK Selin, F Shann, H Whittle. Changing oral to inactivated polio vaccine may increase mortality. Lancet 2016; 387(10023): 1054-5. PMID: 27025182.
KL Flanagan, K Wilson, M Plebanski. Polymorphism in liver stage malaria vaccine candidate proteins: immune evasion and implications for vaccine design. Exp Rev Vaccines 2016; 15(3); 389-99. PMID 26610026.
F Noho-Konteh, JU Adetifa, M Cox, S Hossin, J Reynolds, MT Le, LC Sanyang, A Drammeh, T Forster, P Dickinson, P Ghazal, M Plebanski, H Whittle, SL Rowland-Jones, JS Sutherland, KL Flanagan. Sex-differential non-vaccine specific immunological effects of diphtheria-tetanus-pertussis and measles vaccination. Clin Infect Dis 2016; 63(9): 1213-26. PMID 27436422.
M Steeper, M Plebanski, KL Flanagan. The global challenge of keeping the world’s aging population healthy by vaccination. Trans R Soc Trop Med Hyg 2016; 110(8): 427-31. PMID 27618919.
KL Flanagan and M Plebanski. Sex-differential heterologous (non-specific) effects of vaccines: an emerging public health issue that needs to be understood and exploited. Exp Rev Vaccines 2016; 16(1): 5-13. PMID 27362915.
N Kiraly, JJ Koplin, NW Crawford, KL Flanagan, PG Holt, LC Gurrin, SC Dharmage, KJ Allen Timing of routine infant vaccinations and risk of food allergy and eczema at one year of age. Allergy 2016; 71(4): 541-9. PMID 26707796.
MO Afolabi, AB Tiono, JU Adetifa, JB Yaro, A Drammeh, I Nébié, C Bliss, SH Hodgson, NA Anagnostou, GS Sanou, YJ Jagne, O Ouedraogo, C Tamara, N Ouedraogo, M Ouedraogo, J Njie-Jobe, A Diarra, CJA Duncan, R Cortese, A Nicosia, R Roberts, NK Viebig, O Leroy, AM Lawrie, KL Flanagan, B Kampmann, P Bejon, EB Imoukhuede, KJ Ewer, AVS Hill, K Bojang, SB Sirima. Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African children and infants. Mol Ther 2016; 24(8): 1470-7. PMID 27109630.
KJ Jensen, N Larsen, S Biering-Sørensen, A Andersen, HB Eriksen, I Monteiro, D Hougaard, P Aaby, MG Netea, KL. Flanagan, CS Benn. Heterologous immunological effects of early BCG vaccination in low-birth weight infants in Guinea-Bissau: a randomized-controlled trial. J Infect Dis 2015; 211(6): 956-67.
S Jayasooriya, TI de Silva, J Njie-jobe, C Sanyang, AM Leese, AI Bell, KA McAulay, P Yanchun, HM Long, T Dong, HC Whittle, AB Rickinson, S Rowland-Jones, AD Hislop and KL Flanagan. Early virological and immunological events in asymptomatic Epstein-Barr virus infection in African children. PLoS Pathogens 2015; 11(3): e1004746. PMID 25816224.
K Jensen, J Ndure, M Plebanski, KL Flanagan. Heterologous and sex differential effects of administering vitamin A supplementation with vaccines: a review. Trans Roy Soc Trop Med Hyg 2015; 109(1): 1-2.